A Prospective Study on Drug Prescribing Pattern in Paediatric Patients Presenting with Fever
Background: It is seen that children form one of the largest groups of patients consulting general practitioners. It is reported that 18% of all GP consultations concern children less than 16 years of age every year. Children are constantly changing with respect to growth, psychosocial development and pharmacodynamic response. Children differ from adults in their response to drugs. It is needed to ensure the right drug prescribed and correct dosage is given, especially in the neonatal period.1,2 prompt communication of medication orders minimizes medication errors.
Methods: This study were included 250 IPD cases of Paediatrics wards with complain of fever. This study was conducted in the Department of paediatrics. The duration of study was over a period of one year.
Results: In this study we were included total 250 cases. Among all 36 cases found 1 month to 1 year,123 cases 1-5 year, 91 cases > 5 year. All cases had fever. Among all 100% cases had prescription of antipyretic drug followed by antibiotic 98.8%, antispasmodic 22.4%, analgesic 14.8%, antiemetic14.4%, bronchodilators 13.6%, antiulcer agent 12%,vitamin 6%, cough syrup 4.8%, steroid 0.4%, nasal drop 0.4%, antiallergic 0.4%, purgative 0.4%.
Conclusion: The conclusion of this study that, Irrational FDCs are being commonly prescribed and there is an urgent need to curb these harmful practices by stringent regulations and developing local guidelines for rational prescribing.
2. World Health Organization. Essential medicines and health products. The Pursuit of Responsible Use of Medicines: Sharing and Learning from Country Experiences. Available at: http://www.who.int/medicines/areas/rational_use/en/ [accessed October 12, 2015].
3. Maxwell S. Rational prescribing: the principles of drug selection. Clin Med. 2009;9(5):481–5.
4. Balat JD, Gandhi AM, Patel PP, Dikshit RK. A study of use of fixed dose combinations in Ahmedabad, India. Indian J Pharmacol. 2014;46(5):503–9.
5. Jain NK, Akarte A, Deshmukh PT, Kannojia P, Garud N, Akash Y. Rationality of fixed dose combinations: an Indian scenario. Pharma Res. 2009;1:158–68.
6. World Health Organization. WHO Model List of Essential Medicines for Children 4th list (April 2013)Available at: http://www.who.int/ medicines/publications/essentialmedicines/4th_EMLc_FINAL_- web_8Jul13.pdf [accessed October 12, 2015].
7. Managing Medicines in Schools and Early Years Settings, Dept of Health, March 2005, Available from: www.cornwall.gov.uk/idoc.ashx?docid=06cbd910-09ff...1
8. Prescribing for children, MeReC Bulletin, Vol 11 No 2, 2000. Available from: www.ukmi.nhs.uk/NewMaterial/ html/docs/18060001.pdf
9. Levine SR, Cohen MR, Blanchard NR et al. Guidelines for preventing medication errors in paediatrics. J Paediatr Pharmacol Ther. 2001; 6: 426-42. Available from: http://www.ppag.org/attachments/files/111/Guidelines_Peds.pdf
10. Crocetti M, Moghbeli N, Serwint J. Fever phobia revisited: have parental misconceptions about fever changed in 20 years. Pediatrics. 2001; 107(6):1241–1246
11. Bilenko N, Tessler H, Okbe R, Press J, Gorodischer R. Determinants of antipyretic misuse in children up to 5 years of age: a crosssectional study. Clin Ther. 2006;28(5): 783–793
12. Kramer MS, Naimark L, Leduc DG. Parental fever phobia and its correlates. Pediatrics. 1985;75(6):1110 –1113
13. Li SF, Lacher B, Crain EF. Acetaminophen and ibuprofen dosing by parents. Pediatr Emerg Care. 2000;16(6):394 –397
14. Jaffe DM. Assessment of the child with fever. In: Rudolph CD, Rudolph AM, Hostetter MK, Lister GE, Siegel NJ, eds. Rudolph’s Pediatrics. 21st ed. New York, NY: McGrawHill; 2002:302–309
15. Kohl KS, Marcy SM, Blum M, et al; Brighton Collaboration Fever Working Group. Fever after immunization: current concepts and improved future scientific understanding. Clin Infect Dis. 2004;39(3):389 –394
16. Hasday JD, Garrison A. Antipyretic therapy in patients with sepsis. Clin Infect Dis. 2000; 31(suppl 5):S234 –S241
17. Adam HM. Fever and host responses. Pediatr Rev. 1996;17(9):330 –331
18. Kluger MJ. Fever revisited. Pediatrics. 1992; 90(6):846–850
19. Roberts NJ. Impact of temperature elevation on immunologic defenses. Rev Infect Dis. 1991;13(3):462–272
20. Kumar MA, Ram KT, Ramasamy C. Cross sectional prospective study on drug utilization in an outpatient pediatric department of tertiary care teaching hospital. Global J Pharm. 2013;7(2): 99–102.
21. Gedam DS, Patel U, Verma M, Gedam S, Chourishi A. Drug prescription pattern in pediatric outpatient department in a teaching hospital in central India. Int J Pharm Sci Rev Res. 2012;17(2):42–5.
22. Venkateswaramurthy N, Murali R, Kumar RS. The study of drug utilization pattern in pediatric patients. Int J Pharm Pharm Sci. 2013;5(3):140–4.
23. Indian Academy of Pediatrics Committee on Immunization (IAPCOI). Consensus recommendations on immunization and IAP immunization timetable 2012. Indian Pediatr. 2012;49(7):549–64
Copyright (c) 2021 Harsh Wardhan, Shipra Kaushik, Bithika Ray
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.