Role of Prophylactic Antibiotics and Prevalence of Post-operative Wound Infection in Surgery Department

  • Mukesh Garg Assistant Professor, Department of Surgery, Ananta Institute of Medical Sciences and Research Centre, Rajsamand
Keywords: Surgical Wound Infection, Post-operative, Staphylococcus aureus, Escherichia coli.


Background: the Surgical Wound Infection Task Force changed the term ‘surgical wound infection’ with ‘surgical site infection’. Surgical site infection is defined as superficial site infection and organ or space infection.
Methods: Total 100 cases were involved in this study , 50 for Group A and 50 as Group B. The case control study was carried out in the Departments of Surgery and Microbiology of Ananta Institute of Medical Sciences and Research Centre, Rajsamand. Results: Some associated factors were found such as Anemia Diabetes Mellitus Obesity & Prolonged duration of surgery in group A as well as group B. After post-operative surgery, we found that Staphylococcus aureus most popular organisms which causes infection followed by P. aeruginosa ,K. pneumonia, Escherichia coli.

Conclusion: For surgical-site infections, surgeon should remember local and microbial factors should take appropriate measures to avoid them. One should use the most efficient and the best surgical techniques should try to avoid undue delays in the procedure to prevent postoperative wound infection.


Download data is not yet available.


1. Haley RW, Schaberg DR, Crossley KB, Von Allmen SD, McGowan JE Jr. Extra charges and prolongation of stay attributable to nosocomial infections: a prospective
2. interhospital comparison. Am J Med 1981;70:51-8.
3. Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC
definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Am J Infect Control 1992;20:271-4.
4. Sawyer RG, Pruett TL. Wound infections. Surg Clin North Am 1994;74:519-36.
5. Anderson DJ, Sexton DJ. Epidemiology and pathogenesis of and risk factors for surgical site infection. Up-to-date. 2008. http://www.
6. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection: 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol. 1999;20(4):250-78.
7. Lewis RT, Klein H. Risk factors and post-operative sepsis: Significance of preoperative lymphocytopenia. J Surg Res. 1975;26:365-71.
8. Strachan CJ, Black JP. Prophylactic use of Cefazolin against sepsis
after cholecystectomy. British Journal of Medicine. 1977;l:1254-7.
9. Page CP, Bohnen JM, Fletcher JR. Antimicrobial prophylaxis for surgical wounds: Guidelines for clinical care. Arch Surg. 1993;128:79-
10. Rao AS, Harsha M. Post -operative wound infection. J India Med Assoc
(1975; 44: 90-3)
11. Funary AP, Aerr KJ, Grunkemeier GC, Starr A. Continuous intravenous
insulin infusion reduces the incidence of deep sterna wound infection in diabetic patients after cardiac surgical procedures. Ann Thorac Surg (1999; 67: 352-60)
How to Cite
Garg M. Role of Prophylactic Antibiotics and Prevalence of Post-operative Wound Infection in Surgery Department. Int Arch BioMed Clin Res [Internet]. 2018Jun.29 [cited 2021Nov.27];4(2):187-9. Available from: